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PHILADELPHIA -- Ryan Howard made the Houston Astros pay for pitching to him. Howard singled in the winning run with two outs in the bottom of the 15th inning to lift the Philadelphia Phillies to a 2-1 victory over Houston on Tuesday night. The interleague matchup between teams with two of the four worst records in the majors lasted 5 hours, 5 minutes. Hector Neris (1-0) tossed a perfect inning to earn the win in his major league debut. Grady Sizemore led off the inning against Jake Buchanan (1-2) with a hard one-hop single under second baseman Jose Altuves glove. After Ben Revere sacrificed, Jimmy Rollins flied out and Chase Utley was intentionally walked. Howard then ripped a 1-2 pitch to right and Sizemore slid in safely ahead of right fielder Robbie Grossmans throw. "You go up there with a chip on your shoulder," Howard said. "Them walking Chase, I wanted to get it done." It was the fifth game of at least 14 innings for the Phillies this season, tying a franchise-record first set in 1958. Both starters -- Philadelphias Kyle Kendrick and Houstons Dallas Keuchel -- allowed one run in seven innings. Howard led off the bottom of the second with an opposite-field homer that just cleared the wall in left-centre, giving the Phillies a 1-0 lead. The run snapped a 22-inning scoreless streak for Philadelphia, which was shut out in Washington on Saturday and Sunday. Howards homer was his seventh off lefties in 97 at-bats. He has only 10 against right-handers in 308 at-bats. Howard, who faces an extreme shift to right in all of his at-bats, still hasnt pulled a homer. The struggling slugger is batting just .217 and was benched three straight games last month. "You guys forget what Ive done," the former NL MVP said. "People look at right now. Ive hit balls hard over stretches. All you can do is hit balls hard and once it leaves the bat, its out of your hands." Jon Singletons RBI single in the seventh tied it at 1. The Astros had runners at first and third with no out, but couldnt get the go-ahead run. Matt Dominguez flied out to shallow right and Jake Marisnick grounded into a double play. "A really tough game," Astros manager Bo Porter said. "We just couldnt get the offence going." TRAINERS ROOM Astros: Outfielder George Springer, on the disabled list since July 20 with a strained left quad, made his second rehab appearance at Single-A Quad Cities. Springer could be called up before the series ends Thursday. Phillies: Cliff Lee still hasnt had an MRI on his injured left elbow. ... Left fielder Domonic Brown has an infection in his tonsils and wasnt in the lineup for the fourth straight game. ... UP NEXT Astros: Right-hander Brad Peacock (3-7, 4.93) will come up from Triple-A Oklahoma City to start Wednesday night. Hes replacing Jarred Cosart, who was traded to Miami last week. Peacock gave up seven runs in 3 2-3 innings in his last start on July 23, a 9-7 loss at Oakland. Phillies: Righty David Buchanan (5-5, 4.40) will be recalled from Triple-A Lehigh Valley to take Lees spot. Buchanan has allowed three earned runs or less in his last six major-league starts STARTING TIME Keuchel (10-7) has allowed just two earned runs in his last three starts, but is only 1-1 in that span. The lefty lowered his ERA to 2.89. Kendrick remained 5-11 after giving up five hits in his first quality start in six outings since July 3. Kendrick lowered his ERA to 4.74. HUNTER PENCE HAUNTS The Phillies acquired Pence, an All-Star outfielder, from the Astros on July 29, 2011 for Singleton, Cosart, outfielder Domingo Santana and right-hander Josh Zeid. They were 50-30 at the time and finished with a club-record 102 wins before losing to St. Louis in the NLDS. Pence was traded the following July to San Francisco for outfielder Nate Schierholtz, pitcher Seth Rosin and catcher Tommy Joseph. Clearly, the Astros and Giants were big winners in both trades with the Phillies. SAVE THAT BALL Santana walked with two outs in the 10th, reaching safely for the first time in his career on his 22nd birthday. He was 0 for 13 with 11 strikeouts before drawing a walk. NASTY STUFF Phillies lefty Antonio Bastardo struck out six of the seven batters he faced in the 11th and 12th innings and the Astros fanned a season-high 17 times. Keith Tkachuk Jersey . -- Wichita State is all alone in the record book. Josh Archibald Jersey . “The fact that he was willing to do the deal the way we wanted it to be done showed that he wanted me to be a part of something great," Lowry said, noting that Ujiri willingness to sign off on the proposal that both Lowry and his agent presented to the GM was the final straw that convinced him to return. http://www.officialcoyotesfanstore.com/authentic-niklas-hjalmarsson-coyotes-jersey/ . At 11:06 of the first period, Neal struck Marchand with his knee when Marchand was down on the ice. Marchand remained in the game. Neal was assessed a kneeing penalty for his hit on Marchand. Darcy Kuemper Jersey . Rookie Christian Vazquez got his first three major league hits and drove in three runs, while David Ortiz had three RBIs to break open the game in the sixth inning and lead Boston over the Houston Astros 8-3. Michael Grabner Jersey . Bookies were offering odds of 13/1 before kickoff that the home team Houston Dynamo would prevail by three goals to nil.ORCHARD PARK, N.Y. - Buffalo Bills guard Chris Williams and wide receiver Marquise Goodwin have been ruled out for Sundays game against the Houston Texans.The team announced on Saturday that both players will not make the trip to Houston. They were previously listed as doubtful.Williams, Buffalos starting left guard, has been limited with a back injury since training camp. He exited Buffalos Week 3 loss to San Diego early after aggravating the injury.Rookie Cyril Richardson is expected to receive his first career start in place of Williams. A fiffth-round pick out of Baylor, Richardson worked with the starting unit at left guard during the portions of practice open to the media during the week.ddddddddddddoodwin is out with a concussion. He took a hard hit late in Buffalos loss to the Chargers, but suffered the head injury at Wednesdays practice according to the Bills.Wide receiver Marcus Easley (knee) and linebacker Randell Johnson (linebacker) are also out. Linebacker Keith Rivers (groin), safety DaNorris Searcy (ankle) and cornerback Ron Brooks (illness) are probable. 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